Teenage Cancer Researcher Wins Top Prize At Google Science Fair
MOUNTAIN VIEW, Calif.—A high-school student from Fort Worth, Texas, won top honors July 11 at the first annual Google Science Fair for her project on drug resistance in ovarian cancer. Shree Bose, 17, investigated the connection between an enzyme called AMP-activated protein kinase (AMPK) and resistance to the chemotherapy drug cisplatin. Bose inhibited the activity of AMPK to see how it affected the death of cancer cells. She found that inhibiting AMPK in cells produced two different reactions to cisplatin, depending on whether or not the cells were resistant to the drug....